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Aliskiren/Valsartan, Oral a-lis-KY-ren val_SAR-tan

What are other names for this medicine?

Type of medicine: renin inhibitor/angiotensin II receptor blocker; antihypertensive

Generic and brand names: aliskiren/valsartan, oral; Valturna

What is this medicine used for?

This medicine is taken by mouth to treat high blood pressure.

This medicine may be used for other conditions as determined by your healthcare provider.

What should my healthcare provider know before I take this medicine?

Before you start taking this medicine, tell your healthcare provider if you have ever had:

  • an allergic reaction to any medicine
  • heart failure or heart attack
  • heart valve problems
  • kidney or liver problems
  • imbalances of sodium or potassium in your blood

Tell your healthcare provider if you are on a low-salt diet.

Females of childbearing age: This medicine is not usually given to pregnant women because it can harm the baby. If you are pregnant or if you become pregnant while taking this medicine, contact your healthcare provider right away. Do not become pregnant during treatment with this medicine. Do not breast-feed while you are taking this medicine.

How do I take it?

Check the label on the medicine for directions about your specific dose. Take this medicine exactly as your healthcare provider prescribes. Take it regularly every day even if you feel better. Do not stop taking this medicine without your healthcare provider's approval. You may need to take this medicine for a long time to control your blood pressure. If your provider has also prescribed another medicine, take it regularly.

You may take this medicine with or without food, but you should take it the same way every day. Taking it with meals may lessen the chance the drug will upset your stomach. Taking it with high-fat meals may keep the medicine from being absorbed properly.

What if I miss a dose?

If you miss a dose, take it as soon as you remember unless it is almost time for the next scheduled dose. In that case, skip the missed dose and take the next one as directed. Do not take double doses. If you are not sure of what to do if you miss a dose, or if you miss more than one dose, contact your healthcare provider.

What if I overdose?

If you or anyone else has intentionally taken too much of this medicine, call 911 or go to the emergency room right away. If you pass out, have seizures, weakness or confusion, or have trouble breathing, call 911. If you think that you or anyone else may have taken too much of this medicine, call the poison control center. Do this even if there are no signs of discomfort or poisoning. The poison control center number is 800-222-1222.

Symptoms of an acute overdose may include: fast or slow heartbeat, dizziness, lightheadedness, fainting.

What should I watch out for?

This medicine may make you lightheaded or dizzy. Do not drive or operate machinery unless you are fully alert.

Your healthcare provider will want to see you regularly to check your blood pressure and to adjust your dosage, if necessary. You may need to have lab tests to see how this medicine affects you. Keep all appointments.

This medicine may cause a sudden drop in blood pressure, especially when you first start taking it. You may feel dizzy or faint when you get up quickly after sitting or lying down. Getting up slowly may help. If you feel dizzy or faint while you are standing, lie down for a while and then get up slowly. Also, drinking alcohol may make it worse. Do not drink alcohol unless your healthcare provider approves.

Dizziness may get worse if you lose too much water from your body. You can lose water if you sweat a lot, vomit, or have diarrhea. Tell your provider if you feel dizzy after you have had diarrhea or vomiting. Also, drinking alcohol or taking certain medicines (such as barbiturates or narcotic pain medicines) may make it worse. Do not drink alcohol or take other medicines unless your healthcare provider approves.

If you need emergency care, surgery, or dental work, tell the healthcare provider or dentist you are taking this medicine.

What are the possible side effects?

Along with its needed effects, your medicine may cause some unwanted side effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your healthcare provider if you have any side effects that continue or get worse.

Life-threatening (Report these to your healthcare provider right away. If you cannot reach your healthcare provider right away, get emergency medical care or call 911 for help): Allergic reaction (hives, itching, tightness in your chest, trouble breathing); chest pain; irregular or fast heartbeat; swelling of your face, lips, tongue, or throat; severe dizziness or fainting; trouble swallowing; severe abdominal pain.

Serious (Report these to your healthcare provider right away): Swelling of the face, hands, or feet; yellowish eyes or skin; severe sweating, vomiting, or diarrhea; severe rash.

Other: Headache, dizziness, lightheadedness, tiredness, drowsiness, weakness, nausea, vomiting, diarrhea, heartburn, stomach pain, sore throat, stuffy nose, cough.

What products might interact with this medicine?

When you take this medicine with other medicines, it can change the way this or any of the other medicines work. Nonprescription medicines, vitamins, natural remedies, and certain foods may also interact. Using these products together might cause harmful side effects. Talk to your healthcare provider if you are taking:

  • ACE inhibitors such as benazepril (Lotensin), captopril, enalapril (Vasotec), fosinopril, lisinopril (Prinivil, Zestril), quinapril (Accupril), and ramipril (Altace)
  • alpha blockers such as doxazosin (Cardura) and prazosin (Minipress)
  • angiotensin receptor II blockers such as candesartan (Atacand), eprosartan (Teveten), irbesartan (Avapro), losartan (Cozaar), olmesartan (Benicar), telmisartan (Micardis), and valsartan (Diovan)
  • antiarrhythmics (medicines to treat irregular heartbeat) such as amiodarone (Cordarone, Pacerone) and quinidine
  • antifungals such as itraconazole (Sporanox) and ketoconazole (Nizoral)
  • atorvastatin (Lipitor)
  • beta blockers such as atenolol (Tenormin), bisoprolol (Zebeta), carvedilol (Coreg), labetalol (Trandate), metoprolol (Lopressor, Toprol XL), pindolol, and propranolol (Inderal LA)
  • calcium channel blockers such as amlodipine (Norvasc), diltiazem (Cardizem, Tiazac), felodipine, nifedipine (Procardia, Adalat CC), and verapamil (Calan, Covera-HS, Isoptin SR, Verelan)
  • cyclosporine (Gengraf, Sandimmune, Neoral)
  • diuretics such as amiloride, bumetanide, chlorothiazide (Diuril), eplerenone (Inspra), furosemide (Lasix), hydrochlorothiazide (Microzide), spironolactone (Aldactone), torsemide (Demadex), and triamterene (Dyrenium)
  • natural remedies such as arginine, bayberry, bitter orange, blue cohosh, cayenne, ephedra, gotu kola, cats claw, devils claw, dong quai, garlic, ginger, ginseng, goldenseal, hawthorn, horny goat weed, kelp, ma huang, natural licorice, nettle, and yohimbe
  • lithium (Lithobid)
  • nonsteroidal anti-inflammatory drugs (NSAIDs) such as celecoxib (Celebrex), diclofenac (Voltaren, Cataflam), ibuprofen (Advil, Motrin, Motrin-IB), indomethacin (Indocin), ketoprofen, ketorolac (Toradol), nabumetone (Relafen), naproxen (Aleve, Naprosyn, Anaprox, Naprelan), oxaprozin (Daypro), piroxicam (Feldene), and sulindac (Clinoril)
  • salt substitutes that contain potassium or potassium supplements such as K-Dur, Kaochlor, Kaon, Kaon-Cl, Kay Ciel, Klor-Con, Klorvess, K-Lyte, K-Lor, Micro-K, and Slow-K

Do not drink alcohol while taking this medicine unless your healthcare provider approves.

If you are not sure if your medicines might interact, ask your pharmacist or healthcare provider. Keep a list of all your medicines with you. List all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take. Be sure that you tell all healthcare providers who treat you about all the products you are taking.

How should I store this medicine?

Store this medicine at room temperature. Keep the container tightly closed. Protect it from heat, high humidity, and bright light.


This advisory includes selected information only and may not include all side effects of this medicine or interactions with other medicines. Ask your healthcare provider or pharmacist for more information or if you have any questions.

Ask your pharmacist for the best way to dispose of outdated medicine or medicine you have not used. Do not throw medicine in the trash.

Keep all medicines out of the reach of children.

Do not share medicines with other people.


Developed by RelayHealth.
Medication Advisor 2012.1 published by RelayHealth.
Last modified: 2011-06-20
Last reviewed: 2010-10-11
This content is reviewed periodically and is subject to change as new health information becomes available. The information is intended to inform and educate and is not a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional.
© 2012 RelayHealth and/or its affiliates. All rights reserved.
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