Type of medicine: oxazolidinone antibiotic
Generic and brand names: linezolid, injection; linezolid, oral; Zyvox
This medicine is used to treat serious bacterial infections.
Tell your healthcare provider if you have ever had:
Do not take this medicine if you are have taken an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), and tranylcypromine (Parnate) within the past 2 weeks.
Females of childbearing age: Tell your healthcare provider if you are pregnant or plan to become pregnant. It is not known whether this medicine will harm an unborn baby. Do not breast-feed while taking this medicine without your healthcare provider's approval.
This medicine comes in 3 forms:
Check the label on the medicine for directions about your specific dose. Take this medicine exactly as your healthcare provider prescribes for as long as prescribed. If you stop taking it too soon, the infection may return.
You may take this medicine with or without food. If you have the liquid form of this medicine, gently mix it by turning the bottle upside down 3 to 5 times before you take it. Do not shake the bottle.
If you miss a dose, take it as soon as you remember unless it is almost time for the next scheduled dose. In that case, skip the missed dose and take the next one as directed. Do not take double doses. If you are not sure of what to do if you miss a dose, or if you miss more than one dose, contact your healthcare provider.
If you or anyone else has intentionally taken too much of this medicine, call 911 or go to the emergency room right away. If you pass out, have seizures, weakness or confusion, or have trouble breathing, call 911. If you think that you or anyone else may have taken too much of this medicine, call the poison control center. Do this even if there are no signs of discomfort or poisoning. The poison control center number is 800-222-1222.
Symptoms of an acute overdose may include: weakness, loss of balance.
Lactic acidosis is a rare but serious complication that can occur with use of this medicine. This condition is caused by a buildup of lactic acid in the blood. This happens more often in people with kidney problems. Most people with kidney problems should not take this medicine. The symptoms of lactic acidosis are:
This medicine may cause serotonin syndrome, which can be life-threatening. It may be caused by taking this medicine with other medicines. These medicines include other antidepressants, medicines to treat migraines, pain medicines, some cough medicines, St. John's wort, and others. Make sure that your providers know ALL of the medicines that you take.
Contact your healthcare provider right away if you have:
You need to have blood tests regularly to see how this medicine affects you. Keep all appointments for these tests.
This medicine may cause or worsen diarrhea. If you develop diarrhea while taking this medicine, contact your healthcare provider right away. Do not treat yourself. Some diarrhea medicine will make your diarrhea worse.
This medicine may make you dizzy. Do not drive or operate machinery unless you are fully alert. Drinking alcohol may make it worse. Do not drink alcohol unless your healthcare provider approves.
This medicine may discolor your tongue or teeth. A professional dental cleaning will removed the discoloration.
If your symptoms do not improve within a few days or if they get worse, contact your healthcare provider.
If you need emergency care, surgery, or dental work, tell the healthcare provider or dentist you are taking this medicine.
Along with its needed effects, your medicine may cause some unwanted side effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your healthcare provider if you have any side effects that continue or get worse.
Life-threatening (Report these to your healthcare provider right away. If you cannot reach your healthcare provider right away, get emergency medical care or call 911 for help): Allergic reaction (hives; itching; rash; trouble breathing; tightness in your chest; swelling of your lips, tongue, and throat).
Serious (report these to your healthcare provider right away): Severe nausea, vomiting, or diarrhea; unusual bleeding or bruising; unusual tiredness or weakness; black tarry stool; fast or irregular heartbeat; chest pain; vision changes; fever; unexplained muscle pain; seizures.
Other: Nausea, headache, dizziness, change in sense of taste, white patches in mouth or throat, vaginal discharge, diarrhea, constipation, trouble sleeping.
When you take this medicine with other medicines, it can change the way this or any of the other medicines work. Nonprescription medicines, vitamins, natural remedies, and certain foods may also interact. Using these products together might cause harmful side effects. Talk to your healthcare provider if you are taking:
When taken with certain foods or drinks, this medicine can cause an increase in blood pressure. To avoid this, do not eat large amounts of foods or drink beverages that have a high tyramine content. This includes foods that are aged, fermented, pickled, or smoked, such as aged cheeses; yogurt, dried fruits, smoked fish, meat, or poultry; sauerkraut; soy sauce; red wine; or tap beer. Talk with your healthcare provider about this.
If you are not sure if your medicines might interact, ask your pharmacist or healthcare provider. Keep a list of all your medicines with you. List all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take. Be sure that you tell all healthcare providers who treat you about all the products you are taking.
Store the liquid at room temperature for 21 days. Do not refrigerate. Dispose of any liquid remaining after 21 days. Store the tablets in a tightly closed container at room temperature away from moisture.
This advisory includes selected information only and may not include all side effects of this medicine or interactions with other medicines. Ask your healthcare provider or pharmacist for more information or if you have any questions.
Ask your pharmacist for the best way to dispose of outdated medicine or medicine you have not used. Do not throw medicine in the trash.
Keep all medicines out of the reach of children.
Do not share medicines with other people.
