Type of medicine: antihistamine; antinausea; antiemetic
Generic and brand names: promethazine, injection; promethazine, oral; promethazine, rectal; Phenadoz; Promethacon; Promethegan
This medicine is used to:
This medicine may be used for other conditions as determined by your healthcare provider.
Before taking this medicine, tell your healthcare provider if you have ever had:
Do not take this medicine if you have a history of sleep apnea (when you stop breathing while sleeping and wake up gasping for air). Talk with your healthcare provider about this.
Females of childbearing age: Talk with your healthcare provider if you are pregnant or plan to become pregnant. It is not known whether this medicine will harm an unborn baby. Do not breast-fee while taking this medicine without your healthcare provider's approval.
Check the label on the medicine for directions about your specific dose. Take this medicine exactly as your healthcare provider prescribes. Do not take more of it or take it longer than prescribed.
This medicine comes in the form of tablets and liquid (syrup) for oral use, as suppositories for rectal use, and as injections (shots).
Oral forms of this medicine work best when taken with food or a full glass of milk (8 ounces). If you have the syrup, use a special measuring spoon rather than a common kitchen spoon to make sure you are getting the right dose.
To use a suppository, remove the foil wrapper and moisten the suppository with water. If the suppository is too soft to insert easily, run cold water over it or put it in ice water until it is firm. If it is too dry or hard, moisten it with warm water. Lie on your left side and bend your right knee up toward your chest. Gently push the suppository into your rectum deep enough so that it will not come out.
This medicine may be given by injection (shots) or by IV (through a needle into a large vein).
If you miss a dose, take it as soon as you remember unless it is almost time for the next scheduled dose. In that case, skip the missed dose and take the next one as directed. Do not take double doses. If you are not sure of what to do if you miss a dose, or if you miss more than one dose, contact your healthcare provider.
If you or anyone else has intentionally taken too much of this medicine, call 911 or go to the emergency room right away. If you pass out, have seizures, weakness or confusion, or have trouble breathing, call 911. If you think that you or anyone else may have taken too much of this medicine, call the poison control center. Do this even if there are no signs of discomfort or poisoning. The poison control center number is 800-222-1222.
Symptoms of an acute overdose may include: severe drowsiness, dizziness, dry mouth, large pupils, flushing, nausea, vomiting, shallow breathing, fainting, muscle twitches, loss of balance, seizures.
Never give this medicine to a child without your healthcare provider's approval. It should never be given to children under 2 years of age.
Do not take any prescription or nonprescription antihistamines, sedatives, narcotic analgesics, sleep-producing medicines, tranquilizers, or depressants without your healthcare provider's approval.
While taking this medicine, be careful when you exercise, especially when it is hot. This medicine affects your body's ability to cool down, and you may get too hot. If you get too hot, you might vomit, feel dizzy, have a fast heartbeat, get very stiff muscles, or confused. Contact your provider immediately if you have these symptoms.
Adults over the age of 65 may be at greater risk for side effects. Talk with your provider about this.
This medicine increases the effects of alcohol and other drugs that slow down the nervous system. Do not drink alcohol or take other medicines unless your healthcare provider approves.
This medicine may cause a false reading of some pregnancy tests. Talk with your healthcare provider about this.
This medicine may make you very drowsy. Do not drive or operate machinery unless you are fully alert.
This medicine may make your skin more sensitive to the sun and may cause you to sunburn more easily. While you are taking this medicine, avoid long exposure to the sun. While you are in the sun, wear protective clothing and sunscreen lotion until you know how you will react to the sun. Do not use a sunlamp. If you get a severe sunburn, contact your healthcare provider right away.
Dry mouth is a common side effect of this medicine. Tell your healthcare provider if it becomes bothersome.
Do not take this medicine within 4 days of having a skin test such as an allergy test or a TB test.
If you need emergency care, surgery, or dental work, tell the healthcare provider or dentist you are taking this medicine.
Along with its needed effects, your medicine may cause some unwanted side effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your healthcare provider if you have any side effects that continue or get worse.
Life-threatening (Report these to your healthcare provider right away. If you cannot reach your healthcare provider right away, get emergency medical care or call 911 for help): Allergic reaction (hives; itching; rash; trouble breathing; tightness in your chest; swelling of your lips, tongue, and throat).
Serious (report these to your healthcare provider right away): Rash, sore throat, high fever, excitability, severe drowsiness, flushing, trouble breathing, muscle spasms, twitching in the face and body, confusion, trouble walking, uncontrolled tongue or jaw movement, vision changes, ringing in the ears, trouble urinating, irregular heartbeat, seizures.
Other: Sensitivity to the sun, dry mouth, drowsiness, dizziness, stomach upset, nausea, vomiting, constipation.
When you take this medicine with other medicines, it can change the way this or any of the other medicines work. Nonprescription medicines, vitamins, natural remedies, and certain foods may also interact. Using these products together might cause harmful side effects. Talk to your healthcare provider if you are taking:
If you are not sure if your medicines might interact, ask your pharmacist or healthcare provider. Keep a list of all your medicines with you. List all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take. Be sure that you tell all healthcare providers who treat you about all the products you are taking.
Store this medicine at room temperature. Keep the container tightly closed. Protect it from heat, high humidity, and bright light.
This advisory includes selected information only and may not include all side effects of this medicine or interactions with other medicines. Ask your healthcare provider or pharmacist for more information or if you have any questions.
Ask your pharmacist for the best way to dispose of outdated medicine or medicine you have not used. Do not throw medicines in the trash.
Keep all medicines out of the reach of children.
Do not share medicines with other people.
