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Dapsone, Gel DAP-sohn

What are other names for this medicine?

Type of medicine: sulfone antibiotic

Generic and brand names: dapsone, gel; Aczone

What is this medicine used for?

This medicine is put on the skin to treat acne. It may be used for other conditions as determined by your healthcare provider.

What should my healthcare provider know before I take this medicine?

Before taking this medicine, tell your healthcare provider if you have ever had:

  • an allergic reaction to any medicine
  • blood disorders such as anemia, G6PD, or hemoglobin M

Females of childbearing age: Tell your healthcare provider if you are pregnant or plan to become pregnant. It is not known whether this medicine will harm an unborn baby. Do not breast-feed while taking this medicine without your healthcare provider's approval.

How do I take it?

Check the label on the medicine for directions about your specific dose. Use this medicine exactly as directed by your healthcare provider for the length of time prescribed. Do not take the medicine for any other conditions, even if they seem similar, without your provider's approval.

This medicine is for external use only. Before you use this medicine, wash your skin with mild soap and warm water. Rinse and pat dry with a soft towel.

Put a thin layer of medicine on the area where you need it. Using too much medicine or using it too often can increase the risk of side effects from absorption into your body. Do not bandage or cover the area unless your healthcare provider tells you to do so.

Keep this medicine away from your eyes and mouth. If it gets in your eyes, flush them with water right away.

What if I miss a dose?

If you miss a dose, use it as soon as you remember unless it is almost time for the next scheduled dose. In that case, skip the missed dose and use the next one as directed. Do not use double doses. If you are not sure of what to do if you miss a dose, or if you miss more than one dose, contact your healthcare provider.

What if I overdose?

An acute overdose of this medicine is not likely to cause life-threatening symptoms. If you think that you or anyone else may have taken too much of this medicine, call the poison control center at 800-222-1222.

What should I watch out for?

You may need to have blood tests to see how this medicine affects you. Keep all appointments for these tests.

If your condition does not improve in a few days or if it gets worse, contact your healthcare provider.

If you need emergency care, surgery, or dental work, tell the healthcare provider or dentist you are using this medicine.

What are the possible side effects?

Along with its needed effects, your medicine may cause some unwanted side effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your healthcare provider if you have any side effects that continue or get worse.

Life-threatening (Report these to your healthcare provider right away). If you cannot reach your healthcare provider right away, get emergency medical care or call 911 for help): Allergic reaction (hives; itching; rash; trouble breathing; chest pain or tightness in your chest; swelling of your lips, tongue, and throat).

Serious (report these to your healthcare provider right away): Severe sore throat, severe stomach pain, severe vomiting, severe irritation or rash that starts after you use the medicine.

Other: Dry skin, peeling skin, oily skin.

What products might interact with this medicine?

When you take this medicine with other medicines, it can change the way this or any of the other medicines work. Nonprescription medicines, vitamins, natural remedies, and certain foods may also interact. Using these products together might cause harmful side effects. Talk to your healthcare provider if you are taking:

  • antiseizure medicines such as carbamazepine (Tegretol), phenobarbital, primidone (Mysoline), and phenytoin (Dilantin)
  • para-aminobenzoic acid (PABA)
  • pyrimethamine (Daraprim)
  • rifampin (Rifadin, Rimactane)
  • St. John's wort
  • trimethoprim (Primsol, Trimpex) and trimethoprim/sulfamethoxazole (Bactrim, Septra)

If you are not sure if your medicines might interact, ask your pharmacist or healthcare provider. Keep a list of all your medicines with you. List all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take. Be sure that you tell all healthcare providers who treat you about all the products you are taking.

How should I store this medicine?

Store this medicine at room temperature. Keep the container tightly closed. Protect it from heat, high humidity, and bright light.


This advisory includes selected information only and may not include all side effects of this medicine or interactions with other medicines. Ask your healthcare provider or pharmacist for more information or if you have any questions.

Ask your pharmacist for the best way to dispose of outdated medicine or medicine you have not used. Do not throw medicine in the trash.

Keep all medicines out of the reach of children.

Do not share medicines with other people.


Developed by RelayHealth.
Medication Advisor 2012.1 published by RelayHealth.
Last modified: 2011-01-12
Last reviewed: 2011-01-12
This content is reviewed periodically and is subject to change as new health information becomes available. The information is intended to inform and educate and is not a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional.
© 2012 RelayHealth and/or its affiliates. All rights reserved.
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