Telephone: 

604-548 6688

Fax: 

604-548 6700

Click here 

for Address & Maps

Language:

Difluprednate, Ophthalmic dy-floo-PRED-nate

Thumbnail image of: Eyedrops, How to Put in Eye: Illustration

What are other names for this medicine?

Type of medicine: ophthalmic corticosteroid

Generic and brand names: difluprednate, ophthalmic; Durezol

What is this medicine used for?

This medicine, in the form of eyedrops, is used to treat pain and inflammation of the eyes after eye surgery.

What should my healthcare provider know before I take this medicine?

Before taking this medicine, tell your healthcare provider if you have ever had:

  • an allergic reaction to any medicine or to benzalkonium chloride
  • cataract surgery
  • glaucoma
  • fungal or viral infections of the eyes

Tell your provider if you wear contact lenses.

Females of childbearing age: Talk with your healthcare provider if you are pregnant or plan to become pregnant. It is not known whether this medicine will harm an unborn baby. Do not breast-feed while taking this medicine without your healthcare provider's approval.

How do I use it?

Check the label on the medicine for directions about your specific dose. Follow your healthcare provider's directions carefully. Do not use more or less or use it longer than prescribed. Do not stop using this medicine until your healthcare provider tells you to do so.

If you wear contact lenses, take them out before using this medicine. Ask your healthcare provider if you can put contacts back in after using this medicine.

Shake these eyedrops well each time before you use them.

Wash your hands thoroughly before and after applying the drops. Tilt your head back slightly, and gently pull your lower eyelid down to form a pouch. Hold the dropper directly above your eye, look up, and the number of drops prescribed into the pouch. Close your eye for a minute or two. With a fingertip, press gently on the inside corner of your eye to keep the medicine from draining out.

To keep from contaminating the medicine, do not touch the tip of the dropper to your eye or any other surface. Put the cap on tightly. Do not share eye medicine with other people. If this medicine is contaminated it may cause serious eye infections.

Do not use any other products in your eyes without your healthcare provider’s approval.

What if I miss a dose?

If you miss a dose, use it as soon as you remember unless it is almost time for the next scheduled dose. In that case, skip the missed dose and use the next one as directed. Do not use double doses. If you are not sure of what to do if you miss a dose, or if you miss more than one dose, contact your healthcare provider.

What if I overdose?

An acute overdose of this medicine is not likely to cause life-threatening symptoms. If you think that you or anyone else may have taken too much of this medicine, call the poison control center at 800-222-1222.

What should I watch out for?

Using this medicine for a long time may cause glaucoma (increased pressure in the eyes) or cataracts. Talk with your healthcare provider about this.

Your vision may be blurred for a short time after you apply the drops. Do not drive or operate machinery until you can see clearly.

Tell all providers that you are using these eyedrops before you have lab tests.

If you injure your eye, contact your healthcare provider right away. Eye injuries may be slow to heal while using this medicine.

Do not use other products in your eyes while you are using this medicine without your healthcare provider's approval.

If your condition does not improve in 2 to 3 days or gets worse, contact your healthcare provider.

If you need emergency care, surgery, or dental work, tell the healthcare provider or dentist you are using this medicine.

What are the possible side effects?

Along with its needed effects, your medicine may cause some unwanted side effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your healthcare provider if you have any side effects that continue or get worse.

Life-threatening (Report these to your healthcare provider right away). If you cannot reach your healthcare provider right away, get emergency medical care or call 911 for help): Allergic reaction (hives; itching; rash; trouble breathing; chest pain or tightness in your chest; swelling of your lips, tongue, and throat).

Serious (report these to your healthcare provider right away): Worsening of inflammation, signs of infection, changes in your vision, discharge, eye pain or swelling.

Other: Temporary burning or stinging, dry or red eyes, feeling that something is in your eye, itching, sensitivity to light, blurred vision, headache.

What products might interact with this medicine?

No significant drug interactions have been reported.

If you are not sure if your medicines might interact, ask your pharmacist or healthcare provider. Keep a list of all your medicines with you. List all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take. Be sure that you tell all healthcare providers who treat you about all the products you are taking.

How should I store this medicine?

Store this medicine at room temperature. Do not let it freeze. Keep the container tightly closed. Protect it from heat, high humidity, and bright light.


This advisory includes selected information only and may not include all side effects of this medicine or interactions with other medicines. Ask your healthcare provider or pharmacist for more information or if you have any questions.

Ask your pharmacist for the best way to dispose of outdated medicine or medicine you have not used. Do not throw medicine in the trash.

Keep all medicines out of the reach of children.

Do not share medicines with other people.


Developed by RelayHealth.
Medication Advisor 2012.1 published by RelayHealth.
Last modified: 2010-03-26
Last reviewed: 2010-01-13
This content is reviewed periodically and is subject to change as new health information becomes available. The information is intended to inform and educate and is not a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional.
© 2012 RelayHealth and/or its affiliates. All rights reserved.
Contact KPJ Penang Specialist Hospital Call: 04-548 66 88 Contact Us Online Request an Appointment