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Doxycycline, Oral doks-ih-SY-kleen

What are other names for this medicine?

Type of medicine: tetracycline antibiotic

Generic and brand names: doxycycline, oral; Adoxa; Alodox; Doryx; Doxy 100; Monodox; Ocudox; Vibramycin

What is this medicine used for?

This medicine is an antibiotic that is taken by mouth to treat certain infections and to help control acne. It may also be used to treat other conditions as determined by your healthcare provider. It will not cure viral infections such as colds and the flu.

This medicine is also used to prevent malaria in people traveling to areas where malaria is present. It is also used to prevent traveler's diarrhea.

What should my healthcare provider know before I take this medicine?

Before taking this medicine, tell your healthcare provider if you have ever had:

  • an allergic reaction to any medicine
  • kidney or liver disease
  • lupus
  • trouble swallowing or esophagus problems

Females of childbearing age: This medicine is not usually given to pregnant women because it can harm the baby. Tell your healthcare provider if you are pregnant or plan to become pregnant. Birth control pills may be less effective while you are taking this medicine. Talk to your healthcare provider if you need birth control. Do not become pregnant during treatment with this medicine. If you become pregnant, contact your healthcare provider right away. Do not breast-feed while taking this medicine without discussing with your healthcare provider.

How do I use it?

Check the label on the medicine for directions about your specific dose. Take this medicine exactly as your healthcare provider prescribes. Take it regularly for as long as prescribed, even if you start to feel better. The infection may return if you stop taking the medicine too soon. Do not take more or less than prescribed. Drink plenty of fluids while taking this medicine.

You may take this medicine with or without food. Taking it with meals may lessen the chance the drug will upset your stomach.

If you take this medicine with food to lessen stomach upset, avoid milk and dairy products within 2Â hours of taking this medicine. If you are taking iron medicines or antacids, take them at least 2 hours before or after you take this medicine.

What if I miss a dose?

If you miss a dose, take it as soon as you remember unless it is almost time for the next scheduled dose. In that case, skip the missed dose and take the next one as directed. Do not take double doses. If you are not sure of what to do if you miss a dose, or if you miss more than one dose, contact your healthcare provider.

What if I overdose?

If you or anyone else has intentionally taken too much of this medicine, call 911 or go to the emergency room right away. If you pass out, have seizures, weakness or confusion, or have trouble breathing, call 911. If you think that you or anyone else may have taken too much of this medicine, call the poison control center. Do this even if there are no signs of discomfort or poisoning. The poison control center number is 800-222-1222.

Symptoms of an acute overdose may include: nausea, vomiting, diarrhea, dizziness, increased urination.

What should I watch out for?

This medicine is usually not given to infants or children younger than 8 years old because it can cause problems with tooth development.

Do not take this medicine for other infections unless your healthcare provider approves.

This medicine may make you dizzy. Do not drive or operate machinery unless you are fully alert.

This medicine may cause or worsen diarrhea. If you develop diarrhea while taking this medicine, contact your healthcare provider right away. Do not treat yourself. Some diarrhea medicine will make your diarrhea worse.

You may be more likely to get fungal infections while taking this medicine. Contact your healthcare provider if you notice new symptoms such as white patches in your mouth or a vaginal discharge.

This medicine may make your skin more sensitive to the sun and may cause you to sunburn more easily. While you are taking this medicine, avoid long exposure to the sun. While you are in the sun, wear protective clothing and sunscreen lotion until you know how you will react to the sun. Do not use a sunlamp. If you get a severe sunburn, contact your healthcare provider right away. You may continue to sunburn easily after you stop taking the medicine.

If you need emergency care, surgery, or dental work, tell the healthcare provider or dentist you are taking this medicine.

Diabetics: This medicine may affect urine sugar test results. Talk to your healthcare provider before you change your diet or dosage of diabetes medicine.

What are the possible side effects?

Along with its needed effects, your medicine may cause some unwanted side effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your healthcare provider if you have any side effects that continue or get worse.

Life-threatening (Report these to your healthcare provider right away. If you cannot reach your healthcare provider right away, get emergency medical care or call 911 for help): Allergic reaction (hives; itching; rash; trouble breathing; tightness in your chest; swelling of your lips, tongue, and throat).

Serious (report these to your healthcare provider right away): Trouble swallowing, unusual bruising or bleeding, itchy rash or peeling skin.

Other: White patches in mouth, stomach upset, dizziness, sore mouth, nausea, vomiting, diarrhea, headache.

What products might interact with this medicine?

When you take this medicine with other medicines, it can change the way this or any of the other medicines work. Nonprescription medicines, vitamins, natural remedies, and certain foods may also interact. Using these products together might cause harmful side effects. Talk to your healthcare provider if you are taking:

  • alcohol
  • antacids or vitamins that contain calcium, aluminum, or magnesium (Take at least 2 hours apart from this medicine.)
  • antiseizure medicines such as carbamazepine (Tegretol), phenytoin (Dilantin), mephenytoin (Mesantoin), and ethotoin (Peganone)
  • barbiturates such as phenobarbital and butabarbital (Butisol)
  • birth control pills
  • bismuth subsalicylate (Pepto-Bismol)
  • calcium channel blockers such as diltiazem (Cardizem, Cartia), verapamil (Calan, Isoptin), nifedipine (Procardia, Adalat), nicardipine (Cardene), amlodipine (Norvasc), felodipine
  • cholesterol-lowering medicines such as lovastatin (Mevacor), simvastatin (Zocor), cholestyramine (Questran), and colestipol (Colestid)
  • cimetidine (Tagamet)
  • cyclosporine (Neoral, Sandimmune, Gengraf)
  • didanosine (Videx)
  • digoxin (Lanoxin)
  • ergot medicines such as ergotamine (Ergomar), methysergide (Sansert), and dihydroergotamine (D.H.E. 45)
  • fentanyl (Duragesic, Actiq)
  • lithium (Eskalith, Lithobid)
  • medicines or supplements that contain iron or zinc
  • medicines to treat erectile dysfunction such as sildenafil (Viagra), tadalafil (Cialis), or vardenafil (Levitra)
  • medicines to treat skin problems such as acitretin (Soriatane), isotretinoin, and tretinoin
  • methotrexate (Rheumatrex, Trexall)
  • methoxyflurane (Penthrane)
  • natural remedies such as dong quai and St. John's wort
  • nefazodone
  • penicillin (Pen VK, Vee-tids)
  • quinidine
  • quinapril (Accupril)
  • sucralfate (Carafate)
  • thioridazine
  • triazolam (Halcion)
  • rifampin
  • tacrolimus (Prograf)
  • venlafaxine (Effexor)
  • warfarin (Coumadin)

If you are not sure if your medicines might interact, ask your pharmacist or healthcare provider. Keep a list of all your medicines with you. List all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take. Be sure that you tell all healthcare providers who treat you about all the products you are taking.

How should I store this medicine?

Store this medicine at room temperature. Keep the container tightly closed. Protect it from heat, high humidity, and bright light.


This advisory includes selected information only and may not include all side effects of this medicine or interactions with other medicines. Ask your healthcare provider or pharmacist for more information or if you have any questions.

Ask your pharmacist for the best way to dispose of outdated medicine or medicine you have not used. Do not throw medicine in the trash.

Keep all medicines out of the reach of children.

Do not share medicines with other people.


Developed by RelayHealth.
Medication Advisor 2012.1 published by RelayHealth.
Last modified: 2012-02-02
Last reviewed: 2012-01-03
This content is reviewed periodically and is subject to change as new health information becomes available. The information is intended to inform and educate and is not a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional.
© 2012 RelayHealth and/or its affiliates. All rights reserved.
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