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Galantamine Hydrobromide, Oral ga-LAN-ta-meen hy-droh-BROH-mide

What are other names for this medicine?

Type of medicine: cholinesterase inhibitor

Generic and brand names: galantamine hydrobromide, oral; Razadyne; Razadyne ER

What is this medicine used for?

This medicine is taken by mouth to treat dementia (loss of mental abilities) caused by Alzheimer's disease. It is not a cure, but it may slow the progress of the disease.

This medicine may be used for other conditions as determined by your healthcare provider.

What should my healthcare provider know before I take this medicine?

Tell your healthcare provider if you have ever had:

  • an allergic reaction to any medicine
  • an enlarged prostate gland or trouble urinating
  • an ulcer or intestinal bleeding
  • heart disease or an irregular heartbeat
  • kidney problems
  • liver problems
  • lung disease such as asthma or COPD
  • seizures

Tell your healthcare provider if you smoke or drink alcohol. Alcohol and smoking may increase the risk of ulcers or stomach bleeding. Also be sure to let your provider know if you are taking medicines such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn), aspirin, or products containing aspirin.

Females of childbearing age: Tell your healthcare provider if you are pregnant or plan to become pregnant. Do not breast-feed while taking this medicine without talking with your healthcare provider.

How do I take it?

Check the label on the medicine for directions about your specific dose. Take this medicine exactly as your healthcare provider prescribes. This medicine must be taken regularly every day to be effective. Your healthcare provider will start you on a low dose and gradually increase the dose.

This medicine may come in the form of tablets, extended-release tablets, or liquid. If you have extended-release tablets, do not break, crush, or chew them. Swallow them whole. Ask your pharmacist if you have the extended-release tablets.

Take this medicine with meals to lessen the chance the drug will upset your stomach. Drink plenty of water while you are taking this medicine.

What if I miss a dose?

If you miss a dose, take it as soon as you remember, unless it is almost time for the next scheduled dose. In that case, skip the missed dose and take the next one as directed. Do not take double doses. If you are not sure of what to do if you miss a dose, or if you miss more than one dose, contact your healthcare provider. If you miss several doses, the dosage must be started at a low level again and gradually increased to its previous level.

What if I overdose?

If you or anyone else has intentionally taken too much of this medicine, call 911 or go to the emergency room right away. If you pass out, have seizures, weakness or confusion, or have trouble breathing, call 911. If you think that you or anyone else may have taken too much of this medicine, call the poison control center. Do this even if there are no signs of discomfort or poisoning. The poison control center number is 800-222-1222.

Symptoms of an acute overdose may include: severe nausea, vomiting, stomach cramps, diarrhea, muscle spasms, weakness, watery eyes, drooling, sweating, slow or irregular heartbeat, dizziness, lightheadedness, fainting, seizures.

What should I watch out for?

If you need emergency care, surgery, or dental work, tell the healthcare provider or dentist you are taking this medicine. It may increase the action of drugs they may give you to relax your muscles.

This medicine may make you feel drowsy or dizzy. Do not drive or operate machinery unless you are fully alert. Do not drink alcohol while you are taking this medicine.

Occasionally, this medicine may cause bleeding, ulcers, or perforation of the stomach, small intestine, or large intestine. These problems may occur with or without warning symptoms. If you have abdominal pain, a black tarry stool, or a bloody stool, stop taking this medicine and contact your healthcare provider right away.

If nausea, vomiting, or diarrhea become a problem during treatment with this medicine, your healthcare provider can prescribe some medicine to help.

What are the possible side effects?

Along with its needed effects, your medicine may cause some unwanted effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your healthcare provider if you have any side effects that continue or get worse.

Life-threatening (report these to your healthcare provider right away. If you cannot reach your healthcare provider immediately, get emergency medical care, or call 911 for help): Allergic reaction (hives, itching, rash, tightness in your chest, swelling of your tongue or throat, trouble breathing); seizures; fainting.

Serious (report these to your healthcare provider right away): Slow or irregular heartbeat, trouble urinating, blood in the urine, black or tarry stools, severe stomach cramps.

Other: Nausea, dizziness, vomiting, trouble sleeping, loss of appetite, unexplained weight loss, drowsiness, diarrhea, nervousness.

What products might interact with this medicine?

When you take this medicine with other medicines, it can change the way this or any of the other medicines work. Nonprescription medicines, vitamins, natural remedies, and certain foods may also interact. Using these products together might cause harmful side effects. Talk to your healthcare provider if you are taking:

  • alcohol
  • amitriptyline
  • anticholinergic medicines such as benztropine (Cogentin), clidinium/chlordiazepoxide (Clindex, Librax), combinations (Barbidonna, Donnatal, Kapectolin PG, Relaxadon), dicyclomine (Bentyl), glycopyrrolate (Robinul), hyoscyamine (Levbid, Levsin), oxybutynin (Ditropan), procyclidine (Kemadrin), propantheline (Pro-Banthine), scopolamine (Isopto Hyoscine, Scopace, Transderm Scop), tolterodine (Detrol), trihexyphenidyl (Artane), and trimethobenzamide (Tigan)
  • antiseizure medicines such as carbamazepine (Tegretol) and phenytoin (Dilantin)
  • aspirin or other salicylates
  • cimetidine (Tagamet)
  • ketoconazole (Nizoral)
  • natural remedies such as ginkgo biloba and St. John’s wort
  • nonsteroidal anti-inflammatory medicines (NSAIDs) such as diclofenac (Voltaren, Cataflam), ibuprofen (Motrin, Motrin IB, Advil), indomethacin (Indocin), ketoprofen, ketorolac (Toradol), nabumetone (Relafen), naproxen (Naprosyn, Anaprox, Aleve, Naprelan), oxaprozin (Daypro), piroxicam (Feldene), and sulindac (Clinoril)
  • other medicines for Alzheimer’s disease such as donepezil (Aricept), rivastigmine (Exelon)
  • quinidine
  • SSRI antidepressants such as fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox CR), paroxetine (Paxil), and sertraline (Zoloft)

If you are not sure if your medicines might interact, ask your pharmacist or healthcare provider. Keep a list of all your medicines with you. List all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take. Be sure that you tell all healthcare providers who treat you about all the products you are taking.

How should I store this medicine?

Store this medicine at room temperature. Keep the container tightly closed. Protect it from heat, high humidity, and bright light.


This advisory includes selected information only and may not include all side effects of this medicine or drug interactions with other medicines, Ask your healthcare provider or pharmacist for more information or if you have any questions.

Ask your pharmacist for the best way to dispose of outdated medicine or medicine you have not used. Do not throw medicine in the trash.

Keep all medicines out of the reach of children.

Do not share medicines with other people.


Developed by RelayHealth
Medication Advisor 2012.1 published by RelayHealth.
Last modified: 2011-09-28
Last reviewed: 2010-07-15
This content is reviewed periodically and is subject to change as new health information becomes available. The information is intended to inform and educate and is not a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional.
© 2012 RelayHealth and/or its affiliates. All rights reserved.
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