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Hydroxocobalamin 5 g, Infusion hy-DROKS-oh-koh-BAL-a-min

What are other names for this medicine?

Type of medicine: antidote

Generic and brand names: hydroxocobalamin 5 g, infusion; Cyanokit

What is this medicine used for?

This medicine is given by IV infusion to treat cyanide poisoning.

What should my healthcare provider know before I take this medicine?

Before taking this medicine, the healthcare provider should know if you have ever had:

  • an allergic reaction to any medicine
  • high blood pressure

Females of childbearing age: Talk with your healthcare provider if you are pregnant or plan to become pregnant. It is not known whether this medicine will harm an unborn baby. Do not breast-feed while taking this medicine without your healthcare provider's approval.

How do I use it?

The infusion is given by a healthcare provider.

What should I watch out for?

Your skin may be red for up to 2 weeks after you receive this medicine. After you receive this medicine, avoid long exposure to the sun. Wear protective clothing, a hat, and sunscreen lotion when you need to be outdoors. Do not use a sunlamp. If you get a severe sunburn, contact your healthcare provider right away.

Urine may be red colored for up to 5 weeks after receiving this medicine. This is not blood in the urine and it is not harmful.

You may develop a rash up to 4 weeks after receiving this medicine. The rash usually goes away without treatment within a few weeks. Contact your provider if the rash does not improve or if it gets worse.

If you need emergency care, surgery, or dental work, tell the healthcare provider or dentist you have received this medicine.

What are the possible side effects?

Along with its needed effects, your medicine may cause some unwanted side effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your healthcare provider if you have any side effects that continue or get worse.

Life-threatening (Report these to your healthcare provider right away. If you cannot reach your healthcare provider right away, get emergency medical care or call 911 for help): Allergic reaction (hives; itching; rash; trouble breathing; tightness in your chest; swelling of your lips, tongue, and throat).

Serious (report these to your healthcare provider right away): Severe dizziness, unexplained fever, confusion, anxiety, trouble swallowing.

Other: Mild diarrhea, swelling of feet and ankles, pain at the spot where injection is given, headache, nausea, vomiting, red colored urine, red skin, dry throat, eye irritation or swelling.

What products might interact with this medicine?

No significant drug interactions have been reported.

If you are not sure if your medicines might interact, ask your pharmacist or healthcare provider. Keep a list of all your medicines with you. List all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take. Be sure that you tell all healthcare providers who treat you about all the products you are taking.


This advisory includes selected information only and may not include all side effects of this medicine or interactions with other medicines. Ask your healthcare provider or pharmacist for more information or if you have any questions.

Ask your pharmacist for the best way to dispose of outdated medicine or medicine you have not used. Do not throw medicine in the trash.

Keep all medicines out of the reach of children.

Do not share medicines with other people.


Developed by RelayHealth.
Medication Advisor 2012.1 published by RelayHealth.
Last modified: 2010-03-26
Last reviewed: 2011-08-31
This content is reviewed periodically and is subject to change as new health information becomes available. The information is intended to inform and educate and is not a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional.
© 2012 RelayHealth and/or its affiliates. All rights reserved.
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