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Iloprost Sodium, Inhalation EYE-loh-prost SOH-dee-um

What are other names for this medicine?

Type of medicine: antihypertensive

Generic and brand names: iloprost, inhalation; Ventavis

What is this medicine used for?

This medicine is inhaled through a special nebulizer. It is used to treat pulmonary hypertension (high blood pressure in the lungs).

What should my healthcare provider know before I take this medicine?

Tell your healthcare provider if you have ever had:

  • an allergic reaction to any medicine
  • bleeding or blood clotting problems
  • heart disease
  • low blood pressure
  • kidney or liver disease
  • lung disease such as asthma or COPD

Females of childbearing age: Talk with your healthcare provider if you are pregnant or plan to become pregnant. It is not known whether this medicine will harm an unborn baby. Do not breast-feed while taking this medicine without your healthcare provider's approval.

How do I use it?

Check the label on the medicine for directions about your specific dose. The dose of medicine you take may be increased gradually by your healthcare provider. Do not change your dose or stop using this medicine without your healthcare provider's approval. You will probably need this medicine for a long time (maybe years).

Do not let this medicine come in contact with your skin or eyes. If it does, rinse the skin or your eyes with water right away. Do not drink this medicine.

Do not mix this medicine with any other medicine for inhalation. Do not use the same nebulizer for any other medicine. This medicine should be used only with the nebulizer prescribed by your healthcare provider.

Be sure you know how and when to have nebulizer treatments and how much medicine to use. Read and follow all instructions provided with the nebulizer. It is very important that you use the nebulizer the right way. Do not use this medicine more often than every 2 hours.

If you do not understand how you should prepare or use this medicine, ask your healthcare provider or pharmacist to explain.

What if I overdose?

If you or anyone else has intentionally taken too much of this medicine, call 911 or go to the emergency room right away. If you pass out, have seizures, weakness or confusion, or have trouble breathing, call 911. If you think that you or anyone else may have taken too much of this medicine, call the poison control center. Do this even if there are no signs of discomfort or poisoning. The poison control center number is 800-222-1222.

Symptoms of an acute overdose may include: severe headache, chest pain, reddening of the face, jaw pain, dizziness, nausea, vomiting, diarrhea.

What should I watch out for?

You will need to have blood tests regularly to see how this medicine affects you. Keep all appointments for these tests.

This medicine lowers blood pressure. Taking other blood pressure medicines along with this one may lower your blood pressure too much. Be sure you tell your healthcare provider about all other medicines you take.

You may feel dizzy or faint when you get up quickly after sitting or lying down. Getting up slowly may help. If the fainting gets worse, talk with your healthcare provider. Do not drive or operate machinery unless you are fully alert.

Saunas, hot baths, or sunbathing may cause blood vessels to dilate and lower your blood pressure too far. Be careful when exercising, especially in hot weather. Talk with your healthcare provider about this.

If you need emergency care, surgery, or dental work, tell the healthcare provider or dentist you are taking this medicine.

Do not allow other people to be exposed to this medicine while you are breathing it, especially babies and pregnant women.

What are the possible side effects?

Along with its needed effects, your medicine may cause some unwanted side effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your healthcare provider if you have any side effects that continue or get worse.

Life-threatening (Report these to your healthcare provider right away). If you cannot reach your healthcare provider right away, get emergency medical care or call 911 for help): Allergic reaction (hives; itching; rash; trouble breathing; chest pain or tightness in your chest; swelling of your lips, tongue, and throat).

Serious (report these to your healthcare provider right away): Irregular or rapid heartbeat, severe headache, diarrhea, nausea, vomiting, lightheadedness, chest pain, redness of face or neck, rash, swelling, increased coughing or wheezing, fainting.

Other: Chills, confusion, fever, jaw pain, nervousness, trouble sleeping, muscle or bone pain.

What products might interact with this medicine?

When you take this medicine with other medicines, it can change the way this or any of the other medicines work. Nonprescription medicines, vitamins, natural remedies, and certain foods may also interact. Using these products together might cause harmful side effects. Talk to your healthcare provider if you are taking:

  • ACE inhibitors such as benazepril (Lotensin), captopril, enalapril (Vasotec), fosinopril, lisinopril (Prinivil, Zestril), quinapril (Accupril), and ramipril (Altace)
  • alpha blockers such as doxazosin (Cardura) and prazosin (Minipress)
  • angiotensin receptor II blockers such as candesartan (Atacand), eprosartan (Teveten), irbesartan (Avapro), losartan (Cozaar), olmesartan (Benicar), telmisartan (Micardis), and valsartan (Diovan)
  • aspirin and other salicylates
  • beta blockers such as acebutolol (Sectral), atenolol (Tenormin), carvedilol (Coreg), labetalol (Trandate), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), pindolol, propranolol (Inderal LA), and sotalol (Betapace)
  • medicines to treat or prevent blood clots such as abciximab (ReoPro), argatroban, bivalirudin (Angiomax), clopidogrel (Plavix), dipyridamole (Persantine), eptifibatide (Integrilin), lepirudin (Refludan), tirofiban (Aggrastat), and warfarin (Coumadin)
  • calcium channel blockers such as diltiazem (Cardizem, felodipine, isradipine (DynaCirc CR), nicardipine (Cardene), nifedipine (Adalat CC, Procardia), and verapamil (Calan, Covera-HS, Isoptin SR, Verelan, Tiazac)
  • diuretics (water pills) such as amiloride, bumetanide, chlorothiazide (Diuril), furosemide (Lasix), hydrochlorothiazide (Microzide), spironolactone (Aldactone), torsemide (Demadex), and triamterene (Dyrenium)
  • vasodilators such as hydralazine (Apresoline), isosorbide (Isordil, Imdur, Monoket, ISMO), isoxsuprine, minoxidil, nesiritide (Natrecor), and nitroglycerin

If you are not sure if your medicines might interact, ask your pharmacist or healthcare provider. Keep a list of all your medicines with you. List all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take. Be sure that you tell all healthcare providers who treat you about all the products you are taking.

How should I store this medicine?

Store unopened ampules of this medicine at room temperature. Keep the containers tightly closed. Protect from heat, high humidity, and bright light.


This advisory includes selected information only and may not include all side effects of this medicine or interactions with other medicines. Ask your healthcare provider or pharmacist for more information or if you have any questions.

Ask your pharmacist for the best way to dispose of outdated medicine or medicine you have not used. Do not throw medicine in the trash.

Keep all medicines out of the reach of children.

Do not share medicines with other people.


Developed by RelayHealth.
Medication Advisor 2012.1 published by RelayHealth.
Last modified: 2011-10-03
Last reviewed: 2010-06-02
This content is reviewed periodically and is subject to change as new health information becomes available. The information is intended to inform and educate and is not a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional.
© 2012 RelayHealth and/or its affiliates. All rights reserved.
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