Type of medicine: antidiabetic
Generic and brand names: premixed intermediate-acting and short-acting human insulin, injection; premixed insulin lispro protamine suspension and insulin lispro, injection; premixed insulin aspart and insulin aspart protamine, injection; Humulin 70/30; Humulin 70/30 Prefilled Pen; Novolin 70/30; Humalog Mix 50/50; Humalog Mix 75/25, injection; Humalog Mix 50/50 Prefilled Pen; Humalog Mix 75/25 Prefilled Pen; NovoLog Mix 70/30; NovoLog Mix 70/30 FlexPen
This medicine is given by injection (shots) to treat diabetes mellitus. It helps maintain the proper amount of sugar in the blood.
Before taking this medicine, tell your healthcare provider if you have ever had:
Tell your healthcare provider if you get sick or injured, or if you are scheduled to have surgery.
Females of childbearing age: Tell your healthcare provider if you are pregnant or plan to become pregnant. Do not breast-feed while taking this medicine without your healthcare provider's approval.
This insulin is available in:
This type of insulin will be cloudy in appearance. Rotate the bottle gently before each injection to mix the particles.
This medicine is injected before meals. Talk with your healthcare provider for specific instructions on the best times to give the injections.
Do not mix this insulin with other types of insulin.
Check the label on the medicine for directions about your specific dose. Your healthcare provider will adjust your dosage based on your blood sugar levels. Measure your dosage very carefully to avoid an overdose (insulin shock), which can lead to a coma. Do not stop taking this medicine without your healthcare provider's approval.
Follow exactly any instructions that are supplied with the product your healthcare provider has prescribed. If you do not understand how to use the injection devices or disposable insulin syringes, ask your healthcare provider or pharmacist to demonstrate. Be sure you understand how to set your correct dosage.
These shots are given in your abdomen, upper arm, or thigh. Follow your healthcare provider's instructions carefully regarding dosage and times of injection.
Most people with diabetes give themselves these shots or have someone at home give them. Be sure you know how and when to give them and how much medicine to use.
Follow these steps to inject the insulin from a syringe. Use sterile, disposable syringes and needles. Use them only once and dispose of them safely, following your healthcare provider's instructions.
Wash your hands before using this medicine. Follow these steps to give yourself the shots:
If you are not sure of how to give yourself the shots, ask your healthcare provider or pharmacist for help.
There are several types, strengths, and brands of insulin. Never change the type, strength, or brand of insulin without your healthcare provider's approval.
Ask your healthcare provider what to do if you miss a dose.
If you or anyone else has intentionally taken too much of this medicine, call 911 or go to the emergency room right away. If you pass out, have seizures, weakness or confusion, or have trouble breathing, call 911. If you think that you or anyone else may have taken too much of this medicine, call the poison control center. Do this even if there are no signs of discomfort or poisoning. The poison control center number is 800-222-1222.
Symptoms of an acute overdose may include: extreme weakness, blurred vision, sweating, fruity breath odor, tremors, stomach pain, confusion, seizures, coma.
Follow the diet and exercise program prescribed by your healthcare provider. Eat regular meals and avoid skipping meals, even when you travel or are sick. Your dosage of insulin is based on your food intake. If you do not follow the meal or exercise plan, you may have too much or too little insulin in your blood. Have your blood sugar tested regularly. If your healthcare provider wants you to test your blood sugar at home, follow his or her directions carefully. Depending on the severity of your diabetes, your healthcare provider may want you to check your blood sugar daily using a machine. Follow your healthcare provider's advice exactly.
Alcohol may affect your response to medicine and food. Do not drink alcohol unless your healthcare provider approves.
Low blood sugar (hypoglycemia) can occur if you miss or delay meals, drink too much alcohol, take too much insulin, or exercise more than usual. Symptoms of low blood sugar include confusion, irritability, shaking, weakness, strong hunger, cold sweats, headache, nausea, vision problems, fast heartbeat, and feeling faint. Treat the condition quickly by eating or drinking something with sugar in it such as candy, juice, or nondiet soda. Taking glucose tablets or gels (available in drug stores) is another quick way to treat hypoglycemia.
Contact your healthcare provider if you develop the signs of high blood sugar. Some of the signs of high blood sugar are increased thirst, drowsiness, fruity-smelling breath, flushing, increased urination, and loss of appetite. This can occur if you do not take enough insulin, skip a dose, or do not follow your diet.
If you need emergency care, surgery, or dental work, tell the healthcare provider or dentist you are taking this medicine. Wear some form of ID stating that you are a diabetic (such as a Medic Alert bracelet). If you become unconscious, the ID tells emergency healthcare providers that you are a diabetic and need special care.
Along with its needed effects, your medicine may cause some unwanted side effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your healthcare provider if you have any side effects that continue or get worse.
Life-threatening (Report these to your healthcare provider right away. If you cannot reach your healthcare provider right away, get emergency medical care or call 911 for help): Allergic reaction (hives; itching; rash; trouble breathing; tightness in your chest; swelling of your lips, tongue, and throat).
Serious (report this to your healthcare provider if these symptoms happen often): Symptoms of hypoglycemia (confusion, shaking, weakness, strong hunger, cold sweats, headache, nausea, vision problems, and feeling faint), seizures, fast or irregular heartbeat, swelling of hands or feet, vision changes.
Other: Redness or skin thickening at the spot where an injection has been given, minor rash or itching, weight gain.
When you take this medicine with other medicines, it can change the way this or any of the other medicines work. Nonprescription medicines, vitamins, natural remedies, and certain foods may also interact. Using these products together might cause harmful side effects. Talk to your healthcare provider if you are taking:
Ask your healthcare provider or pharmacist if medicines you are taking are in any of these groups.
Many nonprescription products contain sugar, alcohol, or other ingredients that may interfere with this medicine or increase your blood sugar. Check product labels for warnings for diabetics or ask your healthcare provider or pharmacist for advice.
If you are not sure if your medicines might interact, ask your pharmacist or healthcare provider. Keep a list of all your medicines with you. List all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take. Be sure that you tell all healthcare providers who treat you about all the products you are taking.
Refrigerate unopened vials but do not freeze them. Take insulin out of the refrigerator and allow it to warm to room temperature before using it. Do not expose insulin to very hot temperatures, such as direct sunlight or leave it in a closed, hot car.
Always check the expiration date for insulin. Insulin may be stored at room temperature for up to 28 days or per the package instructions. Mark the bottle with the date it was opened. Discard it after 28 days or per the package instructions, even if the bottle is not empty. Check the package instructions for the proper storage information.
Insulin delivery devices, such as prefilled pens, may be stored in the refrigerator until you use them. Do not let the insulin freeze. Once it is used, keep the device at room temperature. Do not refrigerate the device or pen once it has been used. After you use the insulin delivery device or pen for the first time, it will last for only a certain number of days at room temperature and must then be discarded. Check the package instructions for the proper storage information.
Talk with your healthcare provider or pharmacist if you have any questions about how to store your insulin.
This advisory includes selected information only and may not include all side effects of this medicine or interactions with other medicines. Ask your healthcare provider or pharmacist for more information or if you have any questions.
Ask your pharmacist for the best way to dispose of outdated medicine or medicine you have not used. Do not throw medicines in the trash.
Keep all medicines out of the reach of children.
Do not share medicines with other people.
