Type of medicine: CCR5 antagonist; antiretroviral (anti-HIV)
Generic and brand names: maraviroc, oral; Selzentry
This medicine is taken by mouth to CCR5-tropic treat HIV-1 infection. It is used with other anti-HIV medicines in adults who are already taking anti-HIV medicines and the medicines are not controlling their infection.
Before taking this medicine, tell your healthcare provider if you have ever had:
Tell your healthcare provider if you are taking any medicines that lower your blood pressure.
Females of childbearing age: Tell your healthcare provider if you are pregnant or breast-feeding. Do not breast-feed while taking this medicine without your healthcare provider's approval.
Read the Medication Guide that comes in the medicine package when you start taking this medicine and each time you get a refill.
Check the label on the medicine for directions about your specific dose. Take this medicine exactly as your healthcare provider prescribes. Do not change your dosage on your own. Do not stop taking this medicine without your healthcare provider's approval. If you are not sure of how much and how often to take this medicine, ask your healthcare provider or pharmacist to explain.
Take this medicine with other medicines your healthcare provider prescribes. Follow your healthcare provider's instructions exactly.
You may take this medicine with or without food. Swallow the tablets whole. Do not break, crush, or chew them.
Do not miss any doses. If you do miss a dose, take it as soon as you remember. However, if it is less than 6 hours before your next dose, do not take the missed dose. Wait and take the next dose at the regular time Do not take double doses. If you are not sure of what to do if you miss a dose, or if you miss more than one dose, contact your healthcare provider.
If you or anyone else has intentionally taken too much of this medicine, call 911 or go to the emergency room right away. If you pass out, have seizures, weakness or confusion, or have trouble breathing, call 911. If you think that you or anyone else may have taken too much of this medicine, call the poison control center. Do this even if there are no signs of discomfort or poisoning. The poison control center number is 800-222-1222.
Symptoms of an acute overdose may include: lightheadedness, fainting.
This medicine can cause serious liver problems. An allergic reaction may happen before liver problems occur. Contact your healthcare provider right away if you develop a itchy rash on your skin, yellowing of your eyes or skin, vomiting, or severe abdominal pain.
This medicine is not a cure for HIV infection. You may continue to get illnesses associated with advanced HIV infection, including other infections. There is no evidence that this medicine will reduce the risk of spreading HIV through sexual contact or blood contamination.
You will need to have blood tests regularly to see how this medicine affects you. Keep all appointments for these tests.
This medicine can cause changes in your immune system. It may increase your chance for getting other infections or cancer. Talk with your healthcare provider about this. Tell your healthcare provider if you develop new symptoms after starting your HIV medicines.
If you need emergency care, surgery, or dental work, tell the healthcare provider or dentist you are taking this medicine.
You may feel dizzy or faint when you get up quickly after sitting or lying down. Getting up slowly may help. Do not drive or operate machinery unless you are fully alert.
Do not give this medicine to other people, even if they have the same symptoms you have.
Along with its needed effects, your medicine may cause some unwanted side effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your healthcare provider about any side effects that continue or get worse.
Life-threatening (Report these to your healthcare provider right away. If you cannot reach your healthcare provider right away, get emergency medical care or call 911 for help): Allergic reaction (hives; itching; rash; trouble breathing; tightness in your chest; swelling of your lips, tongue, and throat).
Serious (report these to your healthcare provider right away): Severe stomach pain; yellowing of the eyes or skin; dark urine; light colored bowel movements; rash; severe nausea or vomiting; lightheadedness or fainting; numbness or tingling of the hands or feet; fast, slow, or irregular heartbeat; chest pain.
Other: Headache, fever, cough, fatigue, depression, trouble sleeping, gas, mild nausea, dizziness, joint or muscle pain, constipation.
When you take this medicine with other medicines, it can change the way this or any of the other medicines work. Nonprescription medicines, vitamins, natural remedies, and certain foods may also interact. Using these products together might cause harmful side effects. Talk to your healthcare provider if you are taking:
If you are not sure if your medicines might interact, ask your pharmacist or healthcare provider. Keep a list of all your medicines with you. List all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take. Be sure that you tell all healthcare providers who treat you about all the products you are taking.
Store this medicine at room temperature. Keep the container tightly closed. Protect it from heat, high humidity, and bright light.
This advisory includes selected information only and may not include all side effects of this medicine or interactions with other medicines. Ask your healthcare provider or pharmacist for more information or if you have any questions.
Ask your pharmacist for the best way to dispose of outdated medicine or medicine you have not used. Do not throw medicine in the trash.
Keep all medicines out of the reach of children.
Do not share medicines with other people.
