Type of medicine: 5-HT3 receptor antagonist; antiemetic (antinausea)
Generic and brand names: ondansetron, oral; Zofran ODT; Zuplenz
This medicine is given to prevent nausea and vomiting caused by chemotherapy or radiation therapy.
It is also given to prevent nausea and vomiting after surgery.
Before taking this medicine, tell your healthcare provider if you have ever had:
Also tell your healthcare provider if you take diuretics (water pills), or medicine to control heart rhythms.
Females of childbearing age: Tell your healthcare provider if you are pregnant or plan to become pregnant. Do not breast-feed while taking this medicine without your healthcare provider's approval.
Check the label on the medicine for directions about your specific dose. Take this medicine exactly as your healthcare provider prescribes. Ask your healthcare provider or pharmacist about anything you do not understand.
This medicine is taken by mouth in the form of a liquid, tablet, film, or disintegrating tablet.
If you are taking the orally disintegrating tablet (ODT), do not remove them from blister pack until needed. Peel the backing off the blister pack. Do not push tablet through the packaging. With dry hands, place the tablet on your tongue and allow it to dissolve in your mouth before swallowing.
If you are taking the liquid form of this medicine, use the measuring device that comes with the medicine to measure the doses carefully. Do not use a common kitchen spoon.
If you take the soluble film, make sure your hands are dry before opening the pouch and removing the film. Place the film on your tongue, and let it dissolve. If you need to take more than one film to reach your prescribed dose, let each film dissolve completely before you take another one. If you are taking this medicine to prevent nausea and vomiting due to chemotherapy, take the medicine 30 minutes before receiving your chemotherapy. If you are taking this medicine to prevent nausea and vomiting due to radiation treatment, take the medicine 1 to 2 hours before receiving your radiation treatment or as instructed by your healthcare provider. Sometimes, additional doses of this medicine are taken during chemotherapy or radiation treatment and for 1 to 2 days after the end of your treatment. Take the medicine as directed by your healthcare provider.
If you are taking this medicine to prevent nausea or vomiting after surgery, take it 1Â hour before surgery. Take the exact dose as directed by your healthcare provider.
If you are taking this medicine before chemotherapy, radiation therapy, or surgery as instructed by your healthcare provider, do not miss a dose. If you miss a dose, take it as soon as you remember. If you are not sure of what to do if you miss a dose, contact your healthcare provider.
If you are taking this medicine on a regularly scheduled basis and you miss a dose, take it as soon as you remember unless it is almost time for the next scheduled dose. In that case, skip the missed dose and take the next one as directed. Do not take double doses. If you are not sure of what to do if you miss a dose, or if you miss more than one dose, contact your healthcare provider.
If you or anyone else has intentionally taken too much of this medicine, call 911 or go to the emergency room right away. If you pass out, have seizures, weakness or confusion, or have trouble breathing, call 911. If you think that you or anyone else may have taken too much of this medicine, call the poison control center. Do this even if there are no signs of discomfort or poisoning. The poison control center number is 800-222-1222.
Symptoms of an acute overdose may include: sudden loss of vision; severe constipation; lightheadedness; fainting; fast, slow, or irregular heartbeat.
This medicine may make you dizzy or drowsy. Do not drive or operate machinery unless you are fully alert.
If you need emergency care, surgery, or dental work, tell the healthcare provider or dentist you are taking this medicine.
Along with its needed effects, your medicine may cause some unwanted side effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your healthcare provider if you have any side effects that continue or get worse.
Life-threatening (Report these to your healthcare provider right away. If you cannot reach your healthcare provider right away, get emergency medical care or call 911 for help): Allergic reaction (hives; itching; rash; trouble breathing; tightness in your chest; swelling of your lips, tongue, and throat).
Serious (report these to your healthcare provider right away): Pounding or irregular heartbeat; chest pain; yellowish skin or eyes; trouble urinating.
Other: Headache, dizziness, drowsiness, shivering, nausea, vomiting, tiredness, diarrhea, constipation, stomach pain, pain or redness at the spot where the shots or infusions were given, anxiety, fever.
When you take this medicine with other medicines, it can change the way this or any of the other medicines work. Nonprescription medicines, vitamins, natural remedies, and certain foods may also interact. Using these products together might cause harmful side effects. Talk to your healthcare provider if you are taking:
If you are not sure if your medicines might interact, ask your pharmacist or healthcare provider. Keep a list of all your medicines with you. List all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take. Be sure that you tell all healthcare providers who treat you about all the products you are taking.
Store the tablets or capsules at room temperature. Keep the container tightly closed. Protect it from heat, high humidity, and bright light.
Store the liquid form of this medicine at room temperature. Keep the container tightly closed. Protect it from heat, high humidity, and bright light.
This advisory includes selected information only and may not include all side effects of this medicine or interactions with other medicines. Ask your healthcare provider or pharmacist for more information or if you have any questions.
Keep all medicines out of the reach of children.
Do not share medicines with other people.
