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Pancreatitis, Chronic

Thumbnail image of: Pancreas: Illustration

What is chronic pancreatitis?

Chronic pancreatitis is an ongoing or repeated inflammation of the pancreas.

The pancreas is an organ located behind the stomach. It produces digestive enzymes and insulin. The digestive enzymes flow into the small intestine to help break down food. Insulin is released into the blood to control the level of sugar (glucose) in the blood.

Pancreatitis can be acute or chronic. Acute pancreatitis occurs as 1 sudden episode. After you have had acute pancreatitis, the pancreas usually returns to its normal condition. Chronic pancreatitis means ongoing or repeated bouts of pancreatitis that damage the pancreas. The damaged pancreas gradually becomes unable to make normal digestive enzymes and insulin. It causes frequent attacks of severe pain and can cause life-threatening complications.

What is the cause?

Chronic pancreatitis may result from:

  • drinking too much alcohol (the most common cause)
  • gallstones, which block the normal flow of pancreatic secretions into the intestines
  • too much fat in the blood (a very high triglyceride level)

In rare cases pancreatitis is inherited.

What are the symptoms?

The main symptom of chronic pancreatitis is severe pain in the stomach area that extends to the back. The pain is usually a constant, dull pain that gets worse when you eat or drink. You may notice that it’s worse when you drink alcohol. The pain may lessen when you sit up and lean forward.

As the disease gets worse, attacks of pain last longer and happen more often. Attacks may last a few hours or as long as several weeks.

Other symptoms of chronic pancreatitis include:

  • nausea, vomiting, and diarrhea
  • weight loss
  • fatty or oily stools

As the pancreas gets more damaged, it makes fewer digestive enzymes for the intestines. As a result, your body has trouble digesting food and absorbing the nutrients in the food. Bowel movements get more frequent and smell worse.

If the pancreas is unable to produce the hormone insulin, diabetes may develop, causing these symptoms:

  • increased thirst
  • increased appetite
  • increased urination
  • fatigue
  • weight loss

How is it diagnosed?

Your healthcare provider will ask about your medical history, particularly about how much alcohol you drink and whether you have had gallstones. Your provider will ask about your symptoms and examine you.

You may have the following tests:

  • blood tests, especially to check your blood sugar, amylase, and lipase levels (amylase and lipase are enzymes made by the pancreas)
  • urine tests
  • X-rays of your abdomen and chest
  • ultrasound exam of the pancreas and gallbladder
  • CT scan of the pancreas
  • endoscopic retrograde cholangiopancreatography (ERCP)
  • MRCP

ERCP is a way of looking at your pancreas through a slim flexible tube called an endoscope. The scope is passed through your mouth and stomach to see the area where your pancreas and intestines are connected. MRCP uses an MRI machine to look at the pancreas and gallbladder areas without using an endoscope.

How is it treated?

The goals of treatment are to:

  • Control the pain.
  • Prevent further damage to the pancreas.
  • Prevent more attacks of pancreatitis.

You will need:

  • pain medicine
  • a diet of foods that are easy to digest
  • lots of fluids
  • medicine for nausea and vomiting

If your pancreatitis is severe, you may not be allowed to eat or drink for a few days. In this case you will stay in the hospital so you can be given fluids through your veins (IV).

You may need insulin to control your blood sugar if the pancreas is not producing enough insulin. If the intestine is not getting enough digestive enzymes from the pancreas, you may also need to take enzyme pills to help you digest food.

In some cases your healthcare provider may recommend surgery to help relieve pain or to help the pancreas work better.

If you have alcoholic pancreatitis, no treatment will prevent further pancreatitis or severe abdominal pain if you keep drinking alcohol.

How long will the effects last?

As with any chronic disease, the effects may last for months or years. Your chances for improvement are good if you follow your provider’s treatment plan.

If your pancreatitis is caused by gallbladder disease, treating this problem will make future attacks of pancreatitis less likely. Gallbladder surgery may need to be delayed until the pancreas has recovered from the most recent attack.

If your pancreatitis is caused by high blood fats (triglycerides), treatment will decrease the likelihood of repeat episodes of pancreatitis.

Chronic pancreatitis is a serious disease that can cause long-term poor health, disability, and death. It’s important to follow your healthcare provider’s recommendations for treatment and checkups.

How can I take care of myself?

  • Don’t drink any alcohol. This is the most important thing you can do.
  • Take the medicine prescribed by your healthcare provider.
  • Follow your healthcare provider’s directions for your diet and activity level.
  • Ask your provider:
    • for a diet to keep a healthy weight
    • for a low-fat diet if high blood fats (triglycerides) are a problem
    • whether eating small frequent meals would help you
    • what vitamins or minerals you may need to take
    • if limiting caffeine would help
  • Don’t smoke.

How can I help prevent chronic pancreatitis?

If you drink heavily, get help to stop. Talk to your healthcare provider about referral to an alcohol treatment center or a group like Alcoholics Anonymous.


Developed by RelayHealth.
Adult Advisor 2012.1 published by RelayHealth.
Last modified: 2012-02-01
Last reviewed: 2011-12-01
This content is reviewed periodically and is subject to change as new health information becomes available. The information is intended to inform and educate and is not a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional.
© 2012 RelayHealth and/or its affiliates. All rights reserved.
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