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Pheochromocytoma

What is pheochromocytoma?

A pheochromocytoma is a rare kind of tumor. The tumor usually occurs in one or both adrenal glands, which are located on top of the kidneys. Sometimes it occurs in the thyroid gland or below the diaphragm (the muscle that separates the chest from the abdomen and helps you breathe). You can have more than 1 tumor.

The tumor makes a substance that increases blood pressure. The high blood pressure can cause strokes, sudden death, heart attacks, abnormal heart rhythm, or heart failure.

What are the symptoms?

The tumor may not cause any symptoms. If you do have symptoms, they may include:

  • high blood pressure
  • headache
  • racing heart rate
  • irregular heartbeat
  • sweating spells
  • flushing
  • nausea and vomiting
  • anxiety
  • numbness and tingling of the arms and legs
  • tiredness.

Your healthcare provider may suspect you have the tumor if you:

  • are young and suddenly have high blood pressure
  • have high blood pressure and new or worsening diabetes
  • have huge swings in blood pressure levels when you take medicine or are given anesthesia
  • have a family history of this kind of tumor.

How is it diagnosed?

Your healthcare provider will ask about your medical history and examine you. Tests are needed to confirm the diagnosis. The most common tests are:

  • blood tests
  • urine tests
  • CT (computed tomography) scan
  • MRI (magnetic resonance imaging)
  • MIBG scintiscan, which uses an injection of a radioactive substance and a scanner to look for the tumor.

Some medicines can affect the results of some of these tests. Tell your healthcare provider about all of the medicines you take, including nonprescription drugs.

How is it treated?

There are 3 ways to treat the tumor:

  • surgery
  • chemotherapy
  • radiation therapy.

Surgery to remove all or parts of the thyroid, parathyroid, or adrenal glands is the most common treatment. To prepare for surgery, you will be treated for 7 or more days with medicines that block the bad effects of the substance made by the tumor. You may be in the hospital for a week or two. Your healthcare provider will schedule checkups for several months after the surgery. You may need to take medicines to replace the hormones made by the glands that were removed.

A few pheochromocytomas are cancerous. Chemotherapy uses drugs to kill cancer cells. Chemotherapy may be taken by pill, or it may be put into the body with a needle in the vein or muscle.

Radiation therapy uses high-energy X-rays to shrink tumors.

How long will the effects last?

Most people feel better after the tumor is removed. However, sometimes the tumor comes back. Make sure you keep follow-up checkups with your healthcare provider for long-term monitoring with lab tests.

How can I take care of myself?

  • Keep all follow-up visits with your healthcare provider.
  • Check your blood pressure (or have it checked) as often as your healthcare provider advises.

Written by Donald L. Warkentin, MD.
Adult Advisor 2012.1 published by RelayHealth.
Last modified: 2009-02-11
Last reviewed: 2010-12-17
This content is reviewed periodically and is subject to change as new health information becomes available. The information is intended to inform and educate and is not a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional.
© 2012 RelayHealth and/or its affiliates. All rights reserved.
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