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Podophyllum Resin, Topical poh-DOF-fil-um REZ-in

What are other names for this medicine?

Type of medicine: wart remover

Generic and brand names: podophyllum resin, topical; Podocon-25

What is this medicine used for?

This medicine is a liquid that is put on the skin to treat warts. It may be used for other conditions as determined by your healthcare provider.

What should my healthcare provider know before I take this medicine?

Before taking this medicine, tell your healthcare provider if you have ever had:

  • an allergic reaction to any medicine
  • diabetes
  • problems with blood circulation

Females of childbearing age: Do not take this medicine if you are pregnant. This medicine has been reported to cause birth defects. Stop taking this medicine at the first sign that you may be pregnant and contact your healthcare provider right away. Do not breast-feed while taking this medicine.

How do I use it?

This medicine is applied only by a healthcare provider because it is a poison. It can cause serious side effects if not used properly. Wash off the medicine carefully as instructed by your healthcare provider. It should not be used on moles, birthmarks, or near the eyes. If you get the medicine in your eyes, flush with plenty of water.

What if I overdose?

An acute overdose of this medicine is not likely to cause life-threatening symptoms. If you think that you or anyone else may have taken too much of this medicine, call the poison control center at 800-222-1222.

What should I watch out for?

While some mild to moderate irritation is normal with the use of this medicine, report any severe irritation to your healthcare provider right away.

If you need emergency care, surgery, or dental work, tell the healthcare provider or dentist you are using this medicine.

What are the possible side effects?

Along with its needed effects, your medicine may cause some unwanted side effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your healthcare provider if you have any side effects that continue or get worse.

Life-threatening (Report these to your healthcare provider right away). If you cannot reach your healthcare provider right away, get emergency medical care or call 911 for help): Allergic reaction (hives; itching; rash; trouble breathing; chest pain or tightness in your chest; swelling of your lips, tongue, and throat).

Serious (report these to your healthcare provider right away): Unusual bruising or bleeding, stomach pain, severe skin irritation, severe diarrhea, hallucinations (seeing or hearing things that are not there), fast heartbeat, tingling and numbness, nausea, vomiting, unexplained sore throat and fever, muscle weakness.

Other: Mild rash, flaking, itching, burning, swelling, scabbing at the spot where the cream is applied.

What products might interact with this medicine?

No significant drug interactions have been reported for this medicine.

If you are not sure if your medicines might interact, ask your pharmacist or healthcare provider. Keep a list of all your medicines with you. List all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take. Be sure that you tell all healthcare providers who treat you about all the products you are taking.


This advisory includes selected information only and may not include all side effects of this medicine or interactions with other medicines. Ask your healthcare provider or pharmacist for more information or if you have any questions.

Ask your pharmacist for the best way to dispose of outdated medicine or medicine you have not used. Do not throw medicine in the trash.

Keep all medicines out of the reach of children.

Do not share medicines with other people.


Developed by RelayHealth.
Medication Advisor 2012.1 published by RelayHealth.
Last modified: 2010-03-26
Last reviewed: 2011-01-21
This content is reviewed periodically and is subject to change as new health information becomes available. The information is intended to inform and educate and is not a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional.
© 2012 RelayHealth and/or its affiliates. All rights reserved.
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