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Poliovirus Vaccine, Injection POH-lee-o VY-rus vak-SEEN

What are other names for this medicine?

Type of medicine: vaccine

Generic and brand names: poliovirus vaccine, inactivated, injection; IPOL

What is this medicine used for?

This vaccine is given by injection (shots) to provide protection against polio infection. It is given to infants, children, and adults.

What should my healthcare provider know before I take this medicine?

Before taking this medicine, tell your healthcare provider if you have:

  • an allergic reaction to other vaccine shots or any other medicine
  • a weakened immune system from diseases such as HIV/AIDS or from cancer chemotherapy, radiation therapy, transplant rejection medicine, or steroid medicine

Tell your healthcare provider if you have any infection with fever, diarrhea, or vomiting. If you have a mild cold or mild upper respiratory infection with or without fever, you may still be able to get your shot.

Females of childbearing age: Tell your healthcare provider if you are pregnant or plan to become pregnant. It is not known whether this medicine will harm an unborn baby. Do not breast-feed while receiving this medicine without your healthcare provider's approval.

How do I use it?

The shots are given by your healthcare provider. In children, a total of 4 shots of polio vaccine are given. The shots are usually given at 2 months, 4 months, 6 to 18 months, and 4 to 6 years of age.

This vaccine is not usually given to adults over the age of 18 unless they may are at an increased risk of exposure to poliovirus. Adults who are at risk of exposure include those traveling to areas where polio is common and certain healthcare or laboratory workers. Adults will receive 1 to 3 shots, depending on their previous polio vaccine history.

Your healthcare provider will tell you how many shots you will need and when you should get them. Keep all appointments for vaccinations to be sure that you are protected. If a shot is missed or you get behind schedule, get the missed shot as soon as possible.

This vaccine may be given at the same time as other vaccines. Talk with your healthcare provider about this.

What should I watch out for?

Several doses are needed to fully protect against polio. It is very important to get all of the doses on schedule.

If you need emergency care, surgery, or dental work, tell the healthcare provider or dentist you have received this medicine.

What are the possible side effects?

Along with its needed effects, your medicine may cause some unwanted side effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your healthcare provider if you have any side effects that continue or get worse.

Life-threatening (Report these to your healthcare provider right away. If you cannot reach your healthcare provider right away, get emergency medical care or call 911 for help): Allergic reaction (hives; itching; rash; trouble breathing; tightness in your chest; swelling of your lips, tongue, and throat).

Serious (report these to your healthcare provider right away): Fever over 102°F, seizures.

Other: Redness, swelling or pain where the shot was given; low-grade fever (100.6° to 102°F), loss of appetite, tiredness, irritability, nausea, vomiting.

What products might interact with this medicine?

When you take this medicine with other medicines, it can change the way this or any of the other medicines work. Nonprescription medicines, vitamins, natural remedies, and certain foods may also interact. Using these products together might cause harmful side effects. Tell your healthcare provider if you are taking:

  • adalimumab (Humira) or infliximab (Remicade)
  • anakinra (Kineret)
  • corticosteroids such as betamethasone (Celestone), cortisone, dexamethasone, fludrocortisone (Florinef), hydrocortisone (Cortef, Hydrocortone, A-HydroCort), methylprednisolone (Medrol), prednisone, prednisolone, and triamcinolone (Aristospan, Kenalog)
  • immunosuppressants such as azathioprine (Imuran), cyclosporine (Sandimmune, Neoral, Gengraf), sirolimus (Rapamune), and tacrolimus (Prograf, Protopic)
  • medicines used to treat cancer such as cisplatin, doxorubicin (Adriamycin), hydroxyurea (Hydrea), vinblastine, and vincristine
  • radiation therapy

If you are not sure if your medicines might interact, ask your pharmacist or healthcare provider. Keep a list of all your medicines with you. List all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take. Be sure that you tell all healthcare providers who treat you about all the products you are taking.


This advisory includes selected information only and may not include all side effects of this medicine or interactions with other medicines. Consult your healthcare provider or pharmacist for more information or if you have any questions.

Keep all medicines out of the reach of children.


Developed by RelayHealth.
Medication Advisor 2012.1 published by RelayHealth.
Last modified: 2011-10-13
Last reviewed: 2010-06-08
This content is reviewed periodically and is subject to change as new health information becomes available. The information is intended to inform and educate and is not a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional.
© 2012 RelayHealth and/or its affiliates. All rights reserved.
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