Type of medicine: hormone; infertility treatment
Generic and brand names: progesterone, vaginal; Endometrin
This medicine is inserted in the vagina to help women become pregnant. It may be used for other conditions as determined by your healthcare provider.
Before taking this medicine, tell your healthcare provider if you have ever had:
Tell your healthcare provider if you have recently had a long period of bed rest after major surgery or a broken bone in a cast. Tell your provider if you have a family history of heart disease, heart attack, blood clots, strokes, breast cancer, or other conditions.
Tell your healthcare provider if you smoke. Smoking while you are using this medicine increases the risk of serious side effects such as heart attack, stroke, and blood clots. The risk increases with age and the number of cigarettes smoked a day. Talk to your healthcare provider about ways to quit smoking.
Females of childbearing age: Tell your healthcare provider if you are pregnant or plan to become pregnant. If you think you have become pregnant, contact your healthcare provider right away. Do not breast-feed while taking this medicine without your healthcare provider's approval.
Do not swallow these vaginal inserts. Use this medicine exactly as your healthcare provider prescribes. Do not use more or less or use it longer than prescribed. Ask your healthcare provider about anything you do not understand.
If you miss a dose, use it as soon as you remember unless it is almost time for the next scheduled dose. In that case, skip the missed dose and use the next one as directed. Do not use double doses. If you are not sure of what to do if you miss a dose, or if you miss more than one dose, contact your healthcare provider.
Symptoms of an acute overdose have not been reported.
Rarely, this medicine causes a condition called ovarian hyperstimulation syndrome. The symptoms are severe abdominal bloating and pain, nausea, vomiting, rapid weight gain, shortness of breath, and reduced urination. If you have these symptoms, or if you have burning when you urinate, contact your healthcare provider right away because you need special treatment.
Do not use any other vaginal products or tampons when you are using this medicine.
If you need emergency care or surgery, tell the healthcare provider you are taking this medicine.
Your healthcare provider will want to see you regularly to check your progress. Keep all appointments.
This medicine may cause dizziness or vision problems. Do not drive or operate machinery unless you are fully alert and can see clearly.
Follow your healthcare provider's instructions for recording your body temperature and timing sexual intercourse to increase the likelihood of becoming pregnant.
Along with its needed effects, your medicine may cause some unwanted side effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your healthcare provider if you have any side effects that continue or get worse.
Life-threatening (Report these to your healthcare provider right away. If you cannot reach your healthcare provider right away, get emergency medical care or call 911 for help): Allergic reaction (hives; itching; rash; trouble breathing; tightness in your chest; swelling of your lips, tongue, and throat).
Serious (report these to your healthcare provider right away): Unexplained bleeding from your vagina; sudden severe vomiting, headache, dizziness, or fainting; redness, warmth, or swelling in your lower leg; unusual bruising or bleeding; severe chest pain; sudden vision changes; sudden shortness of breath; yellowing of the skin or eyes, especially with fever, weakness in an arm or leg; trouble speaking.
Other: Hot flashes, breast pain or tenderness, bloating, constipation, vaginal irritation, dizziness, headache, mood swings, nausea, vomiting, drowsiness.
When you take this medicine with other medicines, it can change the way this or any of the other medicines work. Nonprescription medicines, vitamins, natural remedies, and certain foods may also interact. Using these products together might cause harmful side effects. Talk to your healthcare provider if you are taking:
If you are not sure if your medicines might interact, ask your pharmacist or healthcare provider. Keep a list of all your medicines with you. List all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take. Be sure that you tell all healthcare providers who treat you about all the products you are taking.
Store this medicine at room temperature. Keep the container tightly closed. Protect it from heat, high humidity, and bright light.
This advisory includes selected information only and may not include all side effects of this medicine or interactions with other medicines. Ask your healthcare provider or pharmacist for more information or if you have any questions.
Ask your pharmacist for the best way to dispose of outdated medicine or medicine you have not used. Do not throw medicine in the trash.
Keep all medicines out of the reach of children.
Do not share medicines with other people.
