Type of medicine: protease inhibitor (anti-HIV)
Generic and brand names: ritonavir, oral; Norvir Capsules; Norvir Oral Solution; Norvir Tablets
This medicine is taken by mouth to treat HIV-1 infection. It is usually taken with other medicines.
Before taking this medicine, tell your healthcare provider if you have ever had:
Taking this medicine with certain other medicines may be life-threatening. Tell your provider about ALL of the medicines and natural remedies you take, especially antibiotics, sedatives, St. John's Wort, and medicines to treat cholesterol, prostate problems, migraines, mental disorders, or heart rhythm problems.
Males: If you take sildenafil (Viagra), tadalafil (Cialis), or vardenafil (Levitra) while you are taking this medicine, you may be at increased risk of side effects such as low blood pressure, vision changes or priapism (prolonged and painful erections).
Females of childbearing age: Tell your healthcare provider if you are pregnant or plan to become pregnant. Do not breast-feed while taking this medicine.
Hormonal birth control may be less effective while you are taking this medicine. Talk to your healthcare provider if you need birth control.
Check the label on the medicine for directions about your specific dose. Take this medicine exactly as your healthcare provider prescribes. Do not change your dosage on your own. Do not stop taking this medicine without your healthcare provider's approval. If you are not sure of how much and how often to take this medicine, ask your healthcare provider or pharmacist to explain.
Take this medicine with other medicines your healthcare provider prescribes. Follow your healthcare provider's instructions exactly.
Take this medicine with food. This medicine is available in a tablet, capsule, or liquid form.
If you have the liquid form, shake it well before each use. Use the measuring device given to you by the pharmacist to make sure you get the right dose. The average household teaspoon may not hold the right amount of liquid. The liquid form of this medicine can be mixed with chocolate milk, Ensure, or Advera to improve the taste. Take the medicine within 1 hour of mixing with chocolate milk, Ensure, or Advera.
Swallow the tablets whole. Do not chew, crush, or break them.
The tablet and capsule form of this medicine are not the same. Switching from capsules to tablets may cause more nausea, vomiting, stomach pain, and diarrhea for a short time. These symptoms may improve as your body adjusts to the tablets. Talk with your healthcare provider about this.
Do not miss any doses. If you do miss a dose, take it as soon as you remember unless it is almost time for the next scheduled dose. In that case, skip the missed dose and take the next one as directed. Do not take double doses. If you are not sure of what to do if you miss a dose, or if you miss more than one dose, contact your healthcare provider.
If you or anyone else has intentionally taken too much of this medicine, call 911 or go to the emergency room right away. If you pass out, have seizures, weakness or confusion, or have trouble breathing, call 911. If you think that you or anyone else may have taken too much of this medicine, call the poison control center. Do this even if there are no signs of discomfort or poisoning. The poison control center number is 800-222-1222.
Symptoms of an acute overdose may include: dizziness, drowsiness, slurred speech, fainting, trouble walking; numbness or tingling in hands or feet; trouble urinating.
You will need to have blood tests regularly to see how this medicine affects you. Keep all appointments for these tests.
This medicine is not a cure for HIV infection. You may continue to get illnesses associated with advanced HIV infection, including other infections. There is no evidence that this medicine will reduce the risk of spreading HIV through sexual contact or blood contamination.
If you need emergency care, surgery, or dental work, tell the healthcare provider or dentist you are taking this medicine.
Do not give this medicine to other people, even if they have the same symptoms you have.
Your body fat may change as a result of taking this medicine. Your legs and arms may be thin but your chest, belly, back and face may have more fat. Talk with your healthcare provider about this.
Some forms of this medicine contain alcohol. Do not drink alcohol unless your healthcare provider approves.
This medicine may increase the total cholesterol and triglyceride levels in your blood. You will need tests to check these levels regularly. Keep all appointments for tests.
You may develop diabetes when you take this medicine. If you already have diabetes, it may get worse. Talk with your healthcare provider about this.
Diabetics: Your dosage of insulin or medicines taken by mouth for diabetes may need to be changed. If you are controlling your diabetes with diet and exercise, you may need to start taking medicine. Talk to your healthcare provider about this.
Along with its needed effects, your medicine may cause some unwanted side effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your healthcare provider about any side effects that continue or get worse.
Life-threatening (Report these to your healthcare provider right away. If you cannot reach your healthcare provider right away, get emergency medical care or call 911 for help): Allergic reaction (hives; itching; rash; trouble breathing; tightness in your chest; swelling of your lips, tongue, and throat).
Serious (report these to your healthcare provider right away): Severe nausea, vomiting, and abdominal pain; unusual bruising or bleeding; unusual weakness or tiredness; severe diarrhea; yellowing of eyes or skin; dark urine; pale stools; leg pain; tingling or numbness in the hands, feet, or mouth; pounding or irregular heartbeat; chest pain; severe dizziness, lightheadedness, or fainting; increased thirst and urination; severe skin rash, blistering, or peeling; rash with fever, tiredness, muscle or joint aches.
Other: Loss of appetite, mild nausea, vomiting, diarrhea, trouble sleeping, tiredness, headache, change in sense of taste, heartburn, gas.
When you take this medicine with other medicines, it can change the way this or any of the other medicines work. Nonprescription medicines, vitamins, natural remedies, and certain foods may also interact. Using these products together might cause harmful side effects. Talk to your healthcare provider if you are taking:
The effects of this medicine may be increased if you take it with grapefruit juice. Talk with your healthcare provider about this.
If you are not sure if your medicines might interact, ask your pharmacist or healthcare provider. Keep a list of all your medicines with you. List all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take. Be sure that you tell all healthcare providers who treat you about all the products you are taking.
Keep the capsules in the original container and store them in the refrigerator. You may also store the capsules at room temperature, but throw away any unused capsules after 30 days. Protect the capsules from excessive heat and cold.
Store the liquid form of this medicine in the original container at room temperature. Keep the container tightly closed. Do not refrigerate the liquid form. Protect it from heat and bright light.
Store tablets in original container at room temperature. Keep the container tightly closed. If stored outside of original container, throw away any unused medicine after 2 weeks. Protect from moisture or high humidity.
This advisory includes selected information only and may not include all side effects of this medicine or interactions with other medicines. Ask your healthcare provider or pharmacist for more information or if you have any questions.
Ask your pharmacist for the best way to dispose of outdated medicine or medicine you have not used. Do not throw medicine in the trash.
Keep all medicines out of the reach of children.
Do not share medicines with other people.
