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Tetanus Toxoids, Injection TET-a-nus TOKS-oydz

What are other names for this medicine?

Type of medicine: vaccine

Generic and brand names: tetanus toxoids, adsorbed, injection; TT

What is this medicine used for?

This medicine is given by injection (shots) to provide protection against tetanus infection (lockjaw) that may result from wounds or injuries. It is given to persons 7 years of age and older. It is not used to treat an active tetanus infection.

What should my healthcare provider know before I take this medicine?

Before receiving this medicine, tell your healthcare provider if you have ever had:

  • an allergic reaction to any medicine or to latex
  • a bleeding disorder, or if you currently take medicine that reduces the chance of blood clots forming, such as warfarin (Coumadin)
  • a weakened immune system from diseases such as HIV/AIDS or from cancer chemotherapy, radiation therapy, or from taking immunosuppressant medicines to prevent organ transplant rejection or steroid medicines to treat arthritis
  • any problems involving the nervous system, such as seizures

If you are severely ill at the time the shot is scheduled, wait until you recover before getting this vaccine. If you have a mild cold or mild upper respiratory infection with or without fever, you may still be able to get your shot. Tell your healthcare provider if you currently have an infection of any kind.

Females of childbearing age: Tell your healthcare provider if you are pregnant or plan to become pregnant. It is not known whether this medicine will harm an unborn baby. Do not breast-feed while taking this medicine without your healthcare provider's approval.

How do I use it?

These shots are given by a healthcare provider. You will need a series of 3 injections. The first two doses are given 4 to 8 weeks apart, and the third dose is given 6 to 12 months after the second dose. A booster dose is then given every 10 years. Your provider may give you a booster shot if you get a dirty wound and it has been over 5 years since your last shot. Keep all appointments for your shots.

What should I watch out for?

Keep records of your tetanus shots so that any healthcare provider can determine if you need an additional shot after an injury.

This medicine may cause redness, tenderness, and swelling for a few days where you had the injection. If these symptoms don't go away in a couple of days, contact your healthcare provider. A small bump where you had the injection may remain for a few weeks.

If you need emergency care, surgery, or dental work, tell the healthcare provider or dentist you have received this medicine.

What are the possible side effects?

Along with its needed effects, your medicine may cause some unwanted side effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your healthcare provider if you have any side effects that continue or get worse.

Life-threatening (Report these to your healthcare provider right away. If you cannot reach your healthcare provider right away, get emergency medical care or call 911 for help): Allergic reaction (hives; itching; rash; trouble breathing; tightness in your chest; swelling of your lips, tongue, and throat).

Serious (report these to your healthcare provider right away): High fever (over 103°); numbness or tingling in hands or feet; unusual behavior; unusual weakness or tiredness; severe headache; hearing problems; seizures.

Other: Low fever; chills; ill feeling; flushing; aches and pains; itching; nausea; pain, redness, or swelling at the injection site.

What products might interact with this medicine?

When you take this medicine with other medicines, it can change the way this or any of the other medicines work. Nonprescription medicines, vitamins, natural remedies, and certain foods may also interact. Using these products together might cause harmful side effects. Talk to your healthcare provider if you are taking:

  • corticosteroids such as cortisone, dexamethasone, fludrocortisone (Florinef), hydrocortisone (Cortef), methylprednisolone (Medrol), prednisolone (Prelone), prednisone, and triamcinolone (Aristocort)
  • immunosuppressants such as azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Sandimmune, Gengraf, Neoral), glatiramer (Copaxone), mycophenolate (CellCept), sirolimus (Rapamune), and tacrolimus (Prograf)

If you are not sure if your medicines might interact, ask your pharmacist or healthcare provider. Keep a list of all your medicines with you. List all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take. Be sure that you tell all healthcare providers who treat you about all the products you are taking.


This advisory includes selected information only and may not include all side effects of this medicine or interactions with other medicines. Ask your healthcare provider or pharmacist for more information or if you have any questions.

Keep all medicines out of the reach of children.

Do not share medicines with other people.


Developed by RelayHealth.
Medication Advisor 2012.1 published by RelayHealth.
Last modified: 2011-11-18
Last reviewed: 2011-04-08
This content is reviewed periodically and is subject to change as new health information becomes available. The information is intended to inform and educate and is not a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional.
© 2012 RelayHealth and/or its affiliates. All rights reserved.
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