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Tranexamic Acid, Injection tran-eks-AM-ik AS-id

What are other names for this medicine?

Type of medicine: antifibrolytic (bleeding prevention)

Generic and brand names: tranexamic acid, injection; Cyklokapron; Lysteda

What is this medicine used for?

This medicine is given by injection (shots) to people with hemophilia. It is used before and after dental procedures to reduce or prevent bleeding. It may be used for other conditions as determined by your healthcare provider.

What should my healthcare provider know before I take this medicine?

Before taking this medicine, tell your healthcare provider or dentist if you have ever had:

  • an allergic reaction to any medicine
  • a head injury, stroke, or bleeding in the head
  • bleeding or blood clotting problems
  • color blindness or retina problems
  • heart disease
  • kidney disease

Females of childbearing age: Tell your healthcare provider if you are pregnant or plan to become pregnant. Do not breast-feed while taking this medicine without your healthcare provider's approval.

How do I use it?

This medicine is given by a healthcare provider. It is given by IV (slow drip through a needle into a large vein) before a dental procedure and then 3 to 4 times a day for several days. Keep all appointments. Talk with your healthcare provider about how often or how long you will receive this medicine.

What if I miss a dose?

Do not miss any doses. If you miss an appointment for a dose, contact your healthcare provider.

What if I overdose?

If you or anyone else has intentionally taken too much of this medicine, call 911 or go to the emergency room right away. If you pass out, have seizures, weakness or confusion, or have trouble breathing, call 911. If you think that you or anyone else may have taken too much of this medicine, call the poison control center. Do this even if there are no signs of discomfort or poisoning. The poison control center number is 800-222-1222.

Symptoms of an acute overdose may include: nausea, vomiting, lightheadedness.

What should I watch out for?

Your healthcare provider may want you to have an eye exam before starting this medicine and during treatment to determine if this medicine is affecting your eyes. Keep all your appointments.

If you need emergency care, surgery, or dental work, tell the healthcare provider or dentist you have received this medicine.

What are the possible side effects?

Along with its needed effects, your medicine may cause some unwanted side effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your healthcare provider if you have any side effects that continue or get worse.

Life-threatening (Report these to your healthcare provider right away). If you cannot reach your healthcare provider right away, get emergency medical care or call 911 for help): Allergic reaction (hives; itching; rash; trouble breathing; chest pain or tightness in your chest; swelling of your lips, tongue, and throat).

Serious (report these to your healthcare provider): Trouble urinating; severe dizziness or fainting; redness, warmth, or swelling in your legs, hands, ankles or feet; vision changes; severe shortness of breath or coughing; chest pain; sudden headache; problems with speech or walking; sudden confusion, numbness or weakness; seizures.

Other: Nausea, vomiting, diarrhea, sudden mood changes.

What products might interact with this medicine?

When you take this medicine with other medicines, it can change the way this or any of the other medicines work. Nonprescription medicines, vitamins, natural remedies, and certain foods may also interact. Using these products together might cause harmful side effects. Talk to your healthcare provider if you are taking:

  • birth control pills, rings, patches, and implants and hormones such as conjugated estrogens (Premarin), estradiol (Estrace), medroxyprogesterone (Provera), and norethindrone (Aygestin, Camila, Jolivette, Micronor)
  • medicines to treat hemophilia such as Feiba VH, AlphaNine SD, Bebulin, BeneFIX, Mononine, and Profilnine SD
  • tretinoin

If you are not sure if your medicines might interact, ask your pharmacist or healthcare provider. Keep a list of all your medicines with you. List all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take. Be sure that you tell all healthcare providers who treat you about all the products you are taking.


This advisory includes selected information only and may not include all side effects of this medicine or interactions with other medicines. Ask your healthcare provider or pharmacist for more information or if you have any questions.

Ask your pharmacist for the best way to dispose of outdated medicine or medicine you have not used. Do not throw medicine in the trash.

Keep all medicines out of the reach of children.

Do not share medicines with other people.


Developed by RelayHealth.
Medication Advisor 2012.1 published by RelayHealth.
Last modified: 2011-05-17
Last reviewed: 2010-08-16
This content is reviewed periodically and is subject to change as new health information becomes available. The information is intended to inform and educate and is not a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional.
© 2012 RelayHealth and/or its affiliates. All rights reserved.
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